Extended hepatic resection for gallbladder cancer.

Journal Article (Journal Article)

BACKGROUND: Although radical cholecystectomy is the standard of care for gallbladder cancers that invade perimuscular connective tissue or perforate visceral peritoneum, the role of extended right hepatectomy in achieving negative resection margins is not clear. METHODS: Clinicopathologic, perioperative, and long-term outcome data were reviewed from patients who underwent hepatic resection for gallbladder cancer. RESULTS: From 1995 to 2005, 22 consecutive patients underwent hepatic resection for gallbladder cancer, and 11 underwent extended hepatectomy. Negative resection margins were achieved in all patients. There were no significant differences in postoperative morbidity, mortality, and long-term survival after extended and minor hepatectomy. T3 tumors negatively predicted overall and recurrence-free survival. COMMENTS: Extended hepatectomy achieves negative resection margins for patients with gallbladder cancer and is associated with acceptable morbidity and long-term survival.

Full Text

Duke Authors

Cited Authors

  • Reddy, SK; Marroquin, CE; Kuo, PC; Pappas, TN; Clary, BM

Published Date

  • September 2007

Published In

Volume / Issue

  • 194 / 3

Start / End Page

  • 355 - 361

PubMed ID

  • 17693282

Electronic International Standard Serial Number (EISSN)

  • 1879-1883

Digital Object Identifier (DOI)

  • 10.1016/j.amjsurg.2007.02.013


  • eng

Conference Location

  • United States