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Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.

Publication ,  Journal Article
Gupta, RT; Brady, CM; Lotz, J; Boll, DT; Merkle, EM
Published in: AJR Am J Roentgenol
August 2010

OBJECTIVE: The objective of our study was to illustrate how the properties of hepatocyte-specific MR contrast agents can be used in the dynamic evaluation of the biliary system. CONCLUSION: Because of their dual route of excretion through the kidneys and the liver, gadolinium-based, hepatocyte-specific MR contrast agents can be used to evaluate the biliary tract as an off-label use. Images are obtained during the hepatocyte phase, which usually occurs within 20-40 minutes after injection depending on the specific contrast agent selected. Potential uses include showing variant biliary anatomy and choledocholithiasis. Evaluation for acute cholecystitis is possible by assessing for reflux of contrast material across the cystic duct. Additionally, these agents have value in both presurgical and postsurgical imaging for showing anatomy and complications. Finally, these agents are useful in the evaluation of choledochal cysts.

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Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2010

Volume

195

Issue

2

Start / End Page

405 / 413

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Hepatocytes
  • Gadolinium
  • Drug Delivery Systems
  • Contrast Media
  • Biliary Tract Diseases
  • Biliary Tract
 

Citation

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Gupta, R. T., Brady, C. M., Lotz, J., Boll, D. T., & Merkle, E. M. (2010). Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents. AJR Am J Roentgenol, 195(2), 405–413. https://doi.org/10.2214/AJR.09.3641
Gupta, Rajan T., Christopher M. Brady, Joachim Lotz, Daniel T. Boll, and Elmar M. Merkle. “Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.AJR Am J Roentgenol 195, no. 2 (August 2010): 405–13. https://doi.org/10.2214/AJR.09.3641.
Gupta RT, Brady CM, Lotz J, Boll DT, Merkle EM. Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents. AJR Am J Roentgenol. 2010 Aug;195(2):405–13.
Gupta, Rajan T., et al. “Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.AJR Am J Roentgenol, vol. 195, no. 2, Aug. 2010, pp. 405–13. Pubmed, doi:10.2214/AJR.09.3641.
Gupta RT, Brady CM, Lotz J, Boll DT, Merkle EM. Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents. AJR Am J Roentgenol. 2010 Aug;195(2):405–413.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2010

Volume

195

Issue

2

Start / End Page

405 / 413

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Hepatocytes
  • Gadolinium
  • Drug Delivery Systems
  • Contrast Media
  • Biliary Tract Diseases
  • Biliary Tract