Frequency of celiac disease in individuals with Down syndrome in the United States.

Journal Article (Journal Article)

Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.

Full Text

Duke Authors

Cited Authors

  • Mackey, J; Treem, WR; Worley, G; Boney, A; Hart, P; Kishnani, PS

Published Date

  • May 2001

Published In

Volume / Issue

  • 40 / 5

Start / End Page

  • 249 - 252

PubMed ID

  • 11388673

Pubmed Central ID

  • PMC2706421

International Standard Serial Number (ISSN)

  • 0009-9228

Digital Object Identifier (DOI)

  • 10.1177/000992280104000502


  • eng

Conference Location

  • United States