Frequency of celiac disease in individuals with Down syndrome in the United States.
Journal Article (Journal Article)
Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.
Full Text
Duke Authors
Cited Authors
- Mackey, J; Treem, WR; Worley, G; Boney, A; Hart, P; Kishnani, PS
Published Date
- May 2001
Published In
Volume / Issue
- 40 / 5
Start / End Page
- 249 - 252
PubMed ID
- 11388673
Pubmed Central ID
- PMC2706421
International Standard Serial Number (ISSN)
- 0009-9228
Digital Object Identifier (DOI)
- 10.1177/000992280104000502
Language
- eng
Conference Location
- United States