BAEPs in infants with myelomeningocele and later development of Chiari II malformation-related brainstem dysfunction.
Thirty-seven infants with myelomeningocele received brainstem auditory evoked potentials (BAEPs) at a median age of eight days. No infant had brainstem dysfunction at the time of testing. Median follow-up was at 30 months. Of 12 infants who subsequently developed brainstem dysfunction at a median age of three months, 11 had had abnormal neonatal BAEPs. In contrast, only 10 of 25 infants who did not develop brainstem dysfunction had abnormal BAEPs. The mean average I-V interpeak latencies was greater among those who developed symptoms than among those who did not. Neonatal BAEPs can identify a group of asymptomatic infants with myelomeningocele who need close follow-up for the subsequent development of brainstem dysfunction.
Worley, G; Erwin, CW; Schuster, JM; Park, Y; Boyko, OB; Griebel, ML; Weidman, ER; Radtke, RA; Oakes, WJ
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