Epidemiology of methicillin-resistant Staphylococcus aureus.

Journal Article (Journal Article;Review)

The frequency of methicillin-resistant Staphylococcus aureus (MRSA) infections continues to grow in hospital-associated settings and, more recently, in community settings in the United States and globally. The increase in the incidence of infections due to S. aureus is partially a consequence of advances in patient care and also of the pathogen's ability to adapt to a changing environment. Infection due to S. aureus imposes a high and increasing burden on health care resources. A growing concern is the emergence of MRSA infections in patients with no apparent risk factors. MRSA infection in community settings involves considerable morbidity and mortality, as does nosocomial MRSA infection. For community-associated MRSA, person-to-person transmission has been reported, and several factors have been shown to predict disease. We examine the trends in both nosocomial and community-associated MRSA infections and explore recent studies of the mechanisms that allow S. aureus to become resistant to currently available drugs.

Full Text

Duke Authors

Cited Authors

  • Boucher, HW; Corey, GR

Published Date

  • June 1, 2008

Published In

Volume / Issue

  • 46 Suppl 5 /

Start / End Page

  • S344 - S349

PubMed ID

  • 18462089

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1086/533590


  • eng

Conference Location

  • United States