The diagnosis of Plasmodium falciparum infection using a new antigen detection system.

Journal Article (Clinical Trial;Journal Article)

With the widespread emergence of drug-resistant Plasmodium falciparum infection, febrile patients in the tropics can no longer be empirically treated with inexpensive yet effective antimalarials. The substitution of newer and more costly drugs brings with it the need for rapid, accurate, and inexpensive diagnostic procedures so that directed therapy can be used. We report a field trial comparing standard microscopic malaria diagnosis and quantitative buffy coat analysis to a new P. falciparum antigen detection system. The ParaSight F test (PFT) was found to be easy to learn, rapid to perform, and highly accurate. If confirmed, the use of the PFT in endemic areas may aid in the identification of patients requiring therapy for drug-resistant malaria.

Full Text

Duke Authors

Cited Authors

  • Dietze, R; Perkins, M; Boulos, M; Luz, F; Reller, B; Corey, GR

Published Date

  • January 1995

Published In

Volume / Issue

  • 52 / 1

Start / End Page

  • 45 - 49

PubMed ID

  • 7856824

Electronic International Standard Serial Number (EISSN)

  • 1476-1645

International Standard Serial Number (ISSN)

  • 0002-9637

Digital Object Identifier (DOI)

  • 10.4269/ajtmh.1995.52.45


  • eng