Clostridium septicum abscess in hepatic metastases: successful medical management.

Journal Article (Journal Article)

Clostridium septicum bacteremia is frequently associated with hematologic and colonic malignancies and neutropenia. It frequently produces 'metastatic' gangrene with excessive mortality. Standard therapy usually includes surgical debridement and antibiotics. We present a patient with metastatic breast cancer treated with high-dose chemotherapy and bone marrow transplantation. She was treated successfully with antibiotics alone despite developing Cl. septicum bacteremia and gas in hepatic metastases. The pathophysiology of this infection is reviewed.

Full Text

Duke Authors

Cited Authors

  • Thel, MC; Ciaccia, D; Vredenburgh, JJ; Peters, W; Corey, GR

Published Date

  • April 1994

Published In

Volume / Issue

  • 13 / 4

Start / End Page

  • 495 - 496

PubMed ID

  • 7517261

International Standard Serial Number (ISSN)

  • 0268-3369


  • eng

Conference Location

  • England