Influence of the extent of hybridization on the hydrodynamic radius of DNA-functionalized gold nanoparticles.

Journal Article (Journal Article)

A combination of fluorescence spectroscopy and dynamic laser light scattering is used to investigate the relationship between the extent of hybridization on the surface of DNA-functionalized gold nanoparticles and the hydrodynamic radius (Rh) of the nanoparticle. The hydrodynamic radius of the DNA-Au conjugate increases measurably only after approximately 5-10 DNA hybridization events and saturates at its maximum value well before the surface is fully loaded.

Full Text

Duke Authors

Cited Authors

  • Xu, J; Craig, SL

Published Date

  • February 2007

Published In

Volume / Issue

  • 23 / 4

Start / End Page

  • 2015 - 2020

PubMed ID

  • 17279689

Electronic International Standard Serial Number (EISSN)

  • 1520-5827

International Standard Serial Number (ISSN)

  • 0743-7463

Digital Object Identifier (DOI)

  • 10.1021/la0622830


  • eng