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Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin.

Publication ,  Journal Article
Yu, JB; Blitzblau, RC; Patel, SC; Decker, RH; Wilson, LD
Published in: Am J Clin Oncol
April 2010

BACKGROUND: Microcystic adnexal carcinoma (MAC) is a very rare cancer of the skin. It has only been described previously in case reports and small retrospective series. OBJECTIVE: To analyze and summarize data from the National Cancer Institute, Surveillance, Epidemiology, and End Results (SEER) database regarding MAC. METHODS: The SEER 1973 to 2004 database was investigated, and patients with MAC were identified. A statistical analysis was performed. RESULTS: Two hundred twenty-three patients were identified. Predominant site of disease was the head and neck skin (74%). There was only 1 case of recorded metastatic disease. Lymph nodes were pathologically involved in 1%. The 10-year overall survival was 86.4% (Standard Error [SE]: 3.3%). US census population-matched relative survival was 97.7% at 10 years (SE: 5.2%). LIMITATIONS: This study is limited by the retrospective nature of the SEER database. CONCLUSIONS: MAC is locally invasive, and rarely metastasizes to lymph nodes. Overall and population-matched relative survival is excellent.

Duke Scholars

Published In

Am J Clin Oncol

DOI

EISSN

1537-453X

Publication Date

April 2010

Volume

33

Issue

2

Start / End Page

125 / 127

Location

United States

Related Subject Headings

  • Young Adult
  • Treatment Outcome
  • Survival Rate
  • Skin Neoplasms
  • SEER Program
  • Retrospective Studies
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Lymphatic Metastasis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yu, J. B., Blitzblau, R. C., Patel, S. C., Decker, R. H., & Wilson, L. D. (2010). Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin. Am J Clin Oncol, 33(2), 125–127. https://doi.org/10.1097/COC.0b013e31819791eb
Yu, James B., Rachel C. Blitzblau, Sonya C. Patel, Roy H. Decker, and Lynn D. Wilson. “Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin.Am J Clin Oncol 33, no. 2 (April 2010): 125–27. https://doi.org/10.1097/COC.0b013e31819791eb.
Yu, James B., et al. “Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin.Am J Clin Oncol, vol. 33, no. 2, Apr. 2010, pp. 125–27. Pubmed, doi:10.1097/COC.0b013e31819791eb.

Published In

Am J Clin Oncol

DOI

EISSN

1537-453X

Publication Date

April 2010

Volume

33

Issue

2

Start / End Page

125 / 127

Location

United States

Related Subject Headings

  • Young Adult
  • Treatment Outcome
  • Survival Rate
  • Skin Neoplasms
  • SEER Program
  • Retrospective Studies
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Lymphatic Metastasis