Radiation dose-volume effects of optic nerves and chiasm.
Published
Journal Article (Review)
Publications relating radiation toxicity of the optic nerves and chiasm to quantitative dose and dose-volume measures were reviewed. Few studies have adequate data for dose-volume outcome modeling. The risk of toxicity increased markedly at doses >60 Gy at approximately 1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery. The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction. Models of threshold tolerance were examined.
Full Text
Duke Authors
Cited Authors
- Mayo, C; Martel, MK; Marks, LB; Flickinger, J; Nam, J; Kirkpatrick, J
Published Date
- March 1, 2010
Published In
Volume / Issue
- 76 / 3 Suppl
Start / End Page
- S28 - S35
PubMed ID
- 20171514
Pubmed Central ID
- 20171514
Electronic International Standard Serial Number (EISSN)
- 1879-355X
Digital Object Identifier (DOI)
- 10.1016/j.ijrobp.2009.07.1753
Language
- eng
Conference Location
- United States