Infants at risk for sudden infant death syndrome (SIDS): differential prediction for three siblings of SIDS infants.

Journal Article (Journal Article)

The outcome for three siblings of SIDS (SSIDS) infants was predicted, using as a risk model the sleep and respiratory characteristics of a SIDS victim studied extensively during the neonatal period. The SIDS infant had shown unstable state organization and deviant respiration patterns, including a deficit of brief apneic pauses. Like the SIDS infant, the SSIDS infants and a group of 16 normal infants were observed in the home for 7-hr periods when they were 2, 3, 4, and 5 weeks old. Two of the infants showed normal sleep and respiratory characteristics, and they were predicted to develop without respiratory dysfunction. In contrast, the third infant showed a pattern of deviancies similar to the SIDS infant; and at 4 months, she had prolonged apneic episodes, requiring resuscitation on two occasions. The findings are consistent with the notion of subtle central nervous system (CNS) dysfunction in SIDS risk infants from the time of birth.

Full Text

Duke Authors

Cited Authors

  • Thoman, EB; Davis, DH; Graham, S; Scholz, JP; Rowe, JC

Published Date

  • December 1988

Published In

Volume / Issue

  • 11 / 6

Start / End Page

  • 565 - 583

PubMed ID

  • 3252049

Electronic International Standard Serial Number (EISSN)

  • 1573-3521

International Standard Serial Number (ISSN)

  • 0160-7715

Digital Object Identifier (DOI)

  • 10.1007/bf00844906


  • eng