Pathologic apnea and brief respiratory pauses in preterm infants: relation to sleep state.

Journal Article (Journal Article)

The development of pathologic apnea, respiratory pauses, and periodic respiration was examined in 71 high-risk preterm infants, observed weekly. Respiration was recorded every 10 seconds; apnea length and periodic respiration were scored from a tape. All subjects had respiratory pauses, and 36 had pathologic apnea. The mean length of respiratory pauses was longer in quiet sleep, and the frequency of respiratory pauses was greater in active sleep. The mean length of respiratory pauses and probability of pathologic apnea in both sleep states and frequency of pauses in quiet sleep decreased with age. Sex, theophylline treatment, race, and length of mechanical ventilation affected the developmental trajectories of some apnea variables. Apnea in preterm infants cannot be considered a unitary phenomenon.

Duke Authors

Cited Authors

  • Holditch-Davis, D; Edwards, LJ; Wigger, MC

Published Date

  • September 1, 1994

Published In

Volume / Issue

  • 43 / 5

Start / End Page

  • 293 - 300

PubMed ID

  • 7937176

Electronic International Standard Serial Number (EISSN)

  • 1538-9847

International Standard Serial Number (ISSN)

  • 0029-6562


  • eng