Neurophysiologic assessment of brain maturation after an 8-week trial of skin-to-skin contact on preterm infants.

Published

Journal Article

OBJECTIVE:Skin-to-skin contact (SSC) promotes physiological stability and interaction between parents and infants. Analyses of EEG-sleep studies can compare functional brain maturation between SSC and non-SSC cohorts. METHODS:Sixteen EEG-sleep studies were performed on eight preterm infants who received 8 weeks of SSC, and compared with two non-SSC cohorts at term (N=126), a preterm group corrected to term age and a full-term group. Seven linear and two complexity measures were compared (Mann-Whitney U test comparisons p<.05). RESULTS:Fewer REMs, more quiet sleep, increased respiratory regularity, longer cycles, and less spectral beta were noted for SSC preterm infants compared with both control cohorts. Fewer REMs, greater arousals and more quiet sleep were noted for SSC infants compared with the non-SSC preterms at term. Three right hemispheric regions had greater complexity in the SSC group. Discriminant analysis showed that the SSC cohort was closer to the non-SSC full-term cohort. CONCLUSIONS:Skin-to-skin contact accelerates brain maturation in healthy preterm infants compared with two groups without SSC. SIGNIFICANCE:Combined use of linear and complexity analysis strategies offer complementary information regarding altered neuronal functions after developmental care interventions. Such analyses may be helpful to assess other neuroprotection strategies.

Full Text

Duke Authors

Cited Authors

  • Scher, MS; Ludington-Hoe, S; Kaffashi, F; Johnson, MW; Holditch-Davis, D; Loparo, KA

Published Date

  • October 2009

Published In

Volume / Issue

  • 120 / 10

Start / End Page

  • 1812 - 1818

PubMed ID

  • 19766056

Pubmed Central ID

  • 19766056

Electronic International Standard Serial Number (EISSN)

  • 1872-8952

International Standard Serial Number (ISSN)

  • 1388-2457

Digital Object Identifier (DOI)

  • 10.1016/j.clinph.2009.08.004

Language

  • eng