Coagulation 2006: a modern view of hemostasis.
Journal Article (Journal Article;Review)
The authors propose that hemostasis occurs in a stepwise process, regulated by cellular components in vivo. The effectiveness of hemostasis in vivo depends not only on the procoagulant reactions but also on the fibrinolytic process. Causes of coagulopathic bleeding include consumption of coagulation factors and platelets, excessive fibrinolysis, hypothermia, and acidosis. Generation of the right amount of thrombin during the coagulation process not only may be essential for effective hemostasis but also may set the stage for effective wound healing.
Full Text
Duke Authors
Cited Authors
- Hoffman, M; Monroe, DM
Published Date
- February 2007
Published In
Volume / Issue
- 21 / 1
Start / End Page
- 1 - 11
PubMed ID
- 17258114
International Standard Serial Number (ISSN)
- 0889-8588
Digital Object Identifier (DOI)
- 10.1016/j.hoc.2006.11.004
Language
- eng
Conference Location
- United States