Coagulation 2006: a modern view of hemostasis.

Published

Journal Article (Review)

The authors propose that hemostasis occurs in a stepwise process, regulated by cellular components in vivo. The effectiveness of hemostasis in vivo depends not only on the procoagulant reactions but also on the fibrinolytic process. Causes of coagulopathic bleeding include consumption of coagulation factors and platelets, excessive fibrinolysis, hypothermia, and acidosis. Generation of the right amount of thrombin during the coagulation process not only may be essential for effective hemostasis but also may set the stage for effective wound healing.

Full Text

Duke Authors

Cited Authors

  • Hoffman, M; Monroe, DM

Published Date

  • February 2007

Published In

Volume / Issue

  • 21 / 1

Start / End Page

  • 1 - 11

PubMed ID

  • 17258114

Pubmed Central ID

  • 17258114

International Standard Serial Number (ISSN)

  • 0889-8588

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2006.11.004

Language

  • eng

Conference Location

  • United States