Well-differentiated papillary mesothelioma.

Journal Article (Journal Article)

Well-differentiated papillary mesothelioma is an unusual variant of epithelial mesothelioma considered to be of low malignant potential. The majority of previously reported cases developed in the peritoneum of young women without a history of asbestos exposure. The authors report 14 cases of well-differentiated papillary mesothelioma, seven of which originated in the pleura, six in the peritoneum, and one in the tunica vaginalis. Eleven of the patients were male and three were female, with an average age at presentation of 58 years (range 32-82 years). Six of the patients had a quantifiable history of asbestos exposure. Of the nine cases with complete follow-up, six had clinically indolent disease, one showed resolution after adjuvant chemotherapy, one pursued an aggressive course, and one died of other causes. These findings indicate that well-differentiated papillary mesothelioma is a rare variant of mesothelioma with a variable clinical prognosis that is etiologically related to asbestos exposure in some cases.

Full Text

Duke Authors

Cited Authors

  • Butnor, KJ; Sporn, TA; Hammar, SP; Roggli, VL

Published Date

  • October 1, 2001

Published In

Volume / Issue

  • 25 / 10

Start / End Page

  • 1304 - 1309

PubMed ID

  • 11688466

International Standard Serial Number (ISSN)

  • 0147-5185

Digital Object Identifier (DOI)

  • 10.1097/00000478-200110000-00012


  • eng

Conference Location

  • United States