Pituitary microadenoma and primary lymphoma of brain associated with hypothalamic invasion.

Journal Article (Journal Article)

A case of primary histiocytic lymphoma involving the left temporal lobe and hypothalamus is presented. This lesion was associated with a pituitary microadenoma shown immunohistochemically to contain prolactin and with lactational changes in the breasts. The interruption by the neoplasm of neural pathways from cells producing prolactin inhibitory factor in the hypothalamus and increased production of prolactin by the pituitary are suggested as the probable mechanism. The association of lactational changes in the breasts with primary lymphoma of the brain has not been reported.

Full Text

Duke Authors

Cited Authors

  • Roggli, VL; Suzuki, M; Armstrong, D; McGavran, MH

Published Date

  • June 1, 1979

Published In

Volume / Issue

  • 71 / 6

Start / End Page

  • 724 - 727

PubMed ID

  • 377944

International Standard Serial Number (ISSN)

  • 0002-9173

Digital Object Identifier (DOI)

  • 10.1093/ajcp/71.6.724


  • eng

Conference Location

  • England