Thyroid neoplasia following irradiation for medulloblastoma: report of two cases.

Journal Article (Journal Article)

Thyroid neoplasms occurred in two patients 14 and 18 years after treatment with radiation for medulloblastoma. One patient has a papillary cancer and the other patient had multiple adenomas and a Hurthle cell adenoma. In addition, the latter case had foci of hyperplasia plus a microfollicular transformation, which has not been described in association with prior thyroid irradiation. The radiation doses delivered to the thyroid through posterior cervical spinal ports (2000--3000 roentgens) fall within the upper range of radiation dosage associated with induction of neoplastic changes within the thyroid.

Full Text

Duke Authors

Cited Authors

  • Roggli, VL; Estrada, R; Fechner, RE

Published Date

  • June 1, 1979

Published In

Volume / Issue

  • 43 / 6

Start / End Page

  • 2232 - 2238

PubMed ID

  • 455218

International Standard Serial Number (ISSN)

  • 0008-543X

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(197906)43:6<2232::aid-cncr2820430612>;2-u


  • eng

Conference Location

  • United States