Anaerobic resistance of clinical isolates of Staphylococcus aureus to aminoglycosides.


Journal Article

The anaerobic minimum inhibitory concentration of six aminoglycosides (amikacin, gentamicin, kanamycin, netilmicin, sisomicin, and tobramycin) averaged over 10-fold greater than the aerobic minimum inhibitory concentration for 50 clinical isolates of Staphylococcus aureus. Cultures from osteomyelitis and blood generally showed a somewhat greater increase in minimum inhibitory concentration due to anaerobiosis than did cultures from abscesses and wounds, and amikacin activity was most affected by anaerobiosis.

Full Text

Duke Authors

Cited Authors

  • Harrell, LJ; Evans, JB

Published Date

  • December 1, 1978

Published In

Volume / Issue

  • 14 / 6

Start / End Page

  • 927 - 929

PubMed ID

  • 742881

Pubmed Central ID

  • 742881

International Standard Serial Number (ISSN)

  • 0066-4804

Digital Object Identifier (DOI)

  • 10.1128/aac.14.6.927


  • eng

Conference Location

  • United States