Recognition and management of the infant with Beckwith-Wiedemann Syndrome.

Published

Journal Article (Review)

Beckwith-Wiedemann Syndrome (BWS) is the most common overgrowth syndrome in infancy. The characteristic findings are macroglossia, abdominal wall defects, and macrosomia. Genetic studies in infants with BWS demonstrate 3 major subgroups of patients: familial, sporadic, or chromosomally abnormal. Recognition in the neonatal period is important because of the high incidence of childhood malignant tumors associated with BWS. This article provides an overview of the syndrome and discusses its etiology, physical findings, and diagnostic evaluation. Management and clinical implications including family support will also be discussed.

Full Text

Duke Authors

Cited Authors

  • Spivey, PS; Bradshaw, WT

Published Date

  • December 2009

Published In

Volume / Issue

  • 9 / 6

Start / End Page

  • 279 - 285

PubMed ID

  • 20010144

Pubmed Central ID

  • 20010144

Electronic International Standard Serial Number (EISSN)

  • 1536-0911

International Standard Serial Number (ISSN)

  • 1536-0903

Digital Object Identifier (DOI)

  • 10.1097/anc.0b013e3181c2003f

Language

  • eng