Intensity-modulated radiation therapy for anal cancer.

Published

Journal Article (Review)

The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these positive results is the high rate of treatment-related morbidity associated with chemoradiation therapy for anal cancer. The use of intensity-modulated radiation therapy (IMRT) has the potential to reduce acute and chronic treatment-related toxicity, minimize treatment breaks, and potentially improve disease-related outcomes by permitting radiation dose escalation in selected cases.

Full Text

Duke Authors

Cited Authors

  • Czito, BG; Pepek, JM; Meyer, JJ; Yoo, S; Willett, CG

Published Date

  • November 15, 2009

Published In

Volume / Issue

  • 23 / 12

Start / End Page

  • 1082 - 1089

PubMed ID

  • 20017291

Pubmed Central ID

  • 20017291

International Standard Serial Number (ISSN)

  • 0890-9091

Language

  • eng

Conference Location

  • United States