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Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography.

Publication ,  Journal Article
Fleischmann, D; Rubin, GD; Bankier, AA; Hittmair, K
Published in: Radiology
February 2000

PURPOSE: To compare the uniformity of aortoiliac opacification obtained from uniphasic contrast medium injections versus individualized biphasic injections at computed tomographic (CT) angiography. MATERIALS AND METHODS: Thirty-two patients with an abdominal aortic aneurysm underwent CT angiography. In 16 patients (group 1), 120 mL of contrast material was administered at a flow rate of 4 mL/sec. In the other 16 patients (group 2), biphasic injection protocols were computed by using mathematic deconvolution of each patient's time-attenuation response to a standardized test injection. Attenuation uniformity was quantified as the "plateau deviation" of enhancement values, which were calculated as the SD of the time-contiguous attenuation values observed during the 30-second scanning period. RESULTS: Group 2 patients received between 77 and 165 mL (mean, 115 mL) of contrast medium. Initial flow rates ranged from 4.1 to 10.0 mL/sec (mean, 6.8 mL/sec) for the first 4-6 seconds; continuing flow rates ranged from 2.0 to 4.8 mL/sec (mean, 3.1 mL/sec) for the remaining 24-26 seconds. The plateau deviation was significantly smaller in group 2 patients (19 HU) versus group 1 patients (38 HU, P <.001). CONCLUSION: At CT angiography, tailored biphasic injections led to more uniform aortoiliac enhancement, compared with standard uniphasic injections of contrast medium.

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Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

February 2000

Volume

214

Issue

2

Start / End Page

363 / 371

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Time Factors
  • Rheology
  • Radiographic Image Enhancement
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Linear Models
  • Injections, Intravenous
 

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Fleischmann, D., Rubin, G. D., Bankier, A. A., & Hittmair, K. (2000). Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography. Radiology, 214(2), 363–371. https://doi.org/10.1148/radiology.214.2.r00fe18363
Fleischmann, D., G. D. Rubin, A. A. Bankier, and K. Hittmair. “Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography.Radiology 214, no. 2 (February 2000): 363–71. https://doi.org/10.1148/radiology.214.2.r00fe18363.
Fleischmann D, Rubin GD, Bankier AA, Hittmair K. Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography. Radiology. 2000 Feb;214(2):363–71.
Fleischmann, D., et al. “Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography.Radiology, vol. 214, no. 2, Feb. 2000, pp. 363–71. Pubmed, doi:10.1148/radiology.214.2.r00fe18363.
Fleischmann D, Rubin GD, Bankier AA, Hittmair K. Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography. Radiology. 2000 Feb;214(2):363–371.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

February 2000

Volume

214

Issue

2

Start / End Page

363 / 371

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Time Factors
  • Rheology
  • Radiographic Image Enhancement
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Linear Models
  • Injections, Intravenous