Fully automated system for three-dimensional bronchial morphology analysis using volumetric multidetector computed tomography of the chest.

Published

Journal Article

Recent advancements in computed tomography (CT) have enabled quantitative assessment of severity and progression of large airway damage in chronic pulmonary disease. The advent of fast multidetector computed tomography scanning has allowed the acquisition of rapid, low-dose 3D volumetric pulmonary scans that depict the bronchial tree in great detail. Volumetric CT allows quantitative indices of bronchial airway morphology to be calculated, including airway diameters, wall thicknesses, wall area, airway segment lengths, airway taper indices, and airway branching patterns. However, the complexity and size of the bronchial tree render manual measurement methods impractical and inaccurate. We have developed an integrated software package utilizing a new measurement algorithm termed mirror-image Gaussian fit that enables the user to perform automated bronchial segmentation, measurement, and database archiving of the bronchial morphology in high resolution and volumetric CT scans and also allows 3D localization, visualization, and registration.

Full Text

Duke Authors

Cited Authors

  • Venkatraman, R; Raman, R; Raman, B; Moss, RB; Rubin, GD; Mathers, LH; Robinson, TE

Published Date

  • June 2006

Published In

Volume / Issue

  • 19 / 2

Start / End Page

  • 132 - 139

PubMed ID

  • 16341571

Pubmed Central ID

  • 16341571

International Standard Serial Number (ISSN)

  • 0897-1889

Digital Object Identifier (DOI)

  • 10.1007/s10278-005-9240-0

Language

  • eng

Conference Location

  • United States