Although the number of women who relinquish their infants is declining, it is estimated that over 52,000 young women pursue an adoption plan every year. Perinatal nurses practicing in any facet of perinatal care may provide care for a woman implementing an adoption plan for her infant. The provision of care may include interaction with the birthfather, prospective adoptive parents, hospital social worker, and adoption agency or adoption attorney as part of the hospital-based adoption experience. Understanding infant adoption, including the history of adoption in the United States, birthfathers' rights, and knowledge of adoption resources provides nurses with essential information that will allow them to provide appropriate, sensitive, nonjudgmental care to all persons involved in the adoption process.