Prevalence, self-care behaviors, and self-care activities for peripheral neuropathy symptoms of HIV/AIDS.


Journal Article

As part of a larger randomized controlled trial examining the efficacy of an HIV/AIDS symptom management manual (n = 775), this study examined the prevalence of peripheral neuropathy in HIV-infected individuals at 12 sites in the USA, Puerto Rico, and Africa. Neuropathy was reported by 44% of the sample; however, only 29.4% reported initiating self-care behaviors to address the neuropathy symptoms. Antiretroviral therapy was found to increase the frequency of neuropathy symptoms, with an increased mean intensity of 28%. A principal axis factor analysis with Promax rotation was used to assess the relationships in the frequency of use of the 18 self-care activities for neuropathy, revealing three distinct factors: (i) an interactive self-care factor; (ii) a complementary medicine factor; and (iii) a third factor consisting of the negative health items of smoking, alcohol, and street drugs. The study's results suggest that peripheral neuropathy is a common symptom and the presence of neuropathy is associated with self-care behaviors to ameliorate HIV symptoms. The implications for nursing practice include the assessment and evaluation of nursing interventions related to management strategies for neuropathy.

Full Text

Cited Authors

  • Nicholas, PK; Voss, J; Wantland, D; Lindgren, T; Huang, E; Holzemer, WL; Cuca, Y; Moezzi, S; Portillo, C; Willard, S; Arudo, J; Kirksey, K; Corless, IB; Rosa, ME; Robinson, L; Hamilton, MJ; Sefcik, E; Human, S; Rivero-Mendez, M; Maryland, M; Nokes, KM; Eller, L; Kemppainen, J; Dawson-Rose, C; Brion, JM; Bunch, EH; Shannon, M; Nicholas, TP; Viamonte-Ros, A; Bain, CA

Published Date

  • March 2010

Published In

Volume / Issue

  • 12 / 1

Start / End Page

  • 119 - 126

PubMed ID

  • 20487335

Pubmed Central ID

  • 20487335

Electronic International Standard Serial Number (EISSN)

  • 1442-2018

International Standard Serial Number (ISSN)

  • 1441-0745

Digital Object Identifier (DOI)

  • 10.1111/j.1442-2018.2009.00505.x


  • eng