Gliomatosis cerebri presenting with optic nerve involvement: MRI.


Journal Article

Gliomatosis cerebri is a rare form of astrocytoma characterized by extreme infiltration of the brain structure in conjunction with a relative paucity of clinical findings. We describe the MRI findings in a patient with gliomatosis cerebri widely infiltrating the brain who presented with symptoms related to involvement of the optic nerves and chiasm. Contrast-enhanced MRI showed enlargement of the optic nerves and chiasm with pathological enhancement; T2-weighted images showed extensive infiltration of the brain by tumor. Histopathologic examination of the biopsy specimen showed anaplastic astrocytoma with gemistocytic predominance and a diagnosis of gliomatosis cerebri was reached.

Full Text

Duke Authors

Cited Authors

  • Felsberg, GJ; Glass, JP; Tien, RD; McLendon, R

Published Date

  • November 1996

Published In

Volume / Issue

  • 38 / 8

Start / End Page

  • 774 - 777

PubMed ID

  • 8957803

Pubmed Central ID

  • 8957803

International Standard Serial Number (ISSN)

  • 0028-3940

Digital Object Identifier (DOI)

  • 10.1007/s002340050345


  • eng

Conference Location

  • Germany