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Functional significance of striatal responses during episodic decisions: recovery or goal attainment?

Publication ,  Journal Article
Han, S; Huettel, SA; Raposo, A; Adcock, RA; Dobbins, IG
Published in: J Neurosci
March 31, 2010

Memory retrieval is typically a goal-directed behavior, and as such, potentially influenced by reinforcement and motivation processes. Although striatal activation is often evident during memory retrieval, its functional significance remains unclear because typical memory paradigms do not control the motivational significance of memory decisions. We used event-related functional magnetic resonance imaging (fMRI) to investigate striatal activation during recognition with and without performance-linked monetary incentives. During initial performance in the absence of incentives, dorsal striatal activation for "Old" memory conclusions nonetheless exceeded that for "New" conclusions regardless of the accuracy of these conclusions. In contrast, subsequent scans paired incentives with either "Old" or "New" conclusions and demonstrated greater activation for whichever judgment was potentially rewarded, both with and without performance feedback. The data demonstrate that striatal activation during recognition judgments does not signal monetary reward receipt, cognitive feedback, or successful episodic retrieval. Instead, it is heavily dependent upon satisfaction of the subjective goals of the observer.

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Published In

J Neurosci

DOI

EISSN

1529-2401

Publication Date

March 31, 2010

Volume

30

Issue

13

Start / End Page

4767 / 4775

Location

United States

Related Subject Headings

  • Young Adult
  • Reward
  • Neurology & Neurosurgery
  • Motivation
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Individuality
  • Humans
  • Goals
 

Citation

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Han, S., Huettel, S. A., Raposo, A., Adcock, R. A., & Dobbins, I. G. (2010). Functional significance of striatal responses during episodic decisions: recovery or goal attainment? J Neurosci, 30(13), 4767–4775. https://doi.org/10.1523/JNEUROSCI.3077-09.2010
Han, Sanghoon, Scott A. Huettel, Ana Raposo, R Alison Adcock, and Ian G. Dobbins. “Functional significance of striatal responses during episodic decisions: recovery or goal attainment?J Neurosci 30, no. 13 (March 31, 2010): 4767–75. https://doi.org/10.1523/JNEUROSCI.3077-09.2010.
Han S, Huettel SA, Raposo A, Adcock RA, Dobbins IG. Functional significance of striatal responses during episodic decisions: recovery or goal attainment? J Neurosci. 2010 Mar 31;30(13):4767–75.
Han, Sanghoon, et al. “Functional significance of striatal responses during episodic decisions: recovery or goal attainment?J Neurosci, vol. 30, no. 13, Mar. 2010, pp. 4767–75. Pubmed, doi:10.1523/JNEUROSCI.3077-09.2010.
Han S, Huettel SA, Raposo A, Adcock RA, Dobbins IG. Functional significance of striatal responses during episodic decisions: recovery or goal attainment? J Neurosci. 2010 Mar 31;30(13):4767–4775.

Published In

J Neurosci

DOI

EISSN

1529-2401

Publication Date

March 31, 2010

Volume

30

Issue

13

Start / End Page

4767 / 4775

Location

United States

Related Subject Headings

  • Young Adult
  • Reward
  • Neurology & Neurosurgery
  • Motivation
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Individuality
  • Humans
  • Goals