Getting to the root of plant biology: impact of the Arabidopsis genome sequence on root research.

Published

Journal Article (Review)

Prior to the availability of the genome sequence, the root of Arabidopsis had attracted a small but ardent group of researchers drawn to its accessibility and developmental simplicity. Roots are easily observed when grown on the surface of nutrient agar media, facilitating analysis of responses to stimuli such as gravity and touch. Developmental biologists were attracted to the simple radial organization of primary root tissues, which form a series of concentric cylinders around the central vascular tissue. Equally attractive was the mode of propagation, with stem cells at the tip giving rise to progeny that were confined to cell files. These properties of root development reduced the normal four-dimensional problem of development (three spatial dimensions and time) to a two-dimensional problem, with cell type on the radial axis and developmental time along the longitudinal axis. The availability of the complete Arabidopsis genome sequence has dramatically accelerated traditional genetic research on root biology, and has also enabled entirely new experimental strategies to be applied. Here we review examples of the ways in which availability of the Arabidopsis genome sequence has enhanced progress in understanding root biology.

Full Text

Duke Authors

Cited Authors

  • Benfey, PN; Bennett, M; Schiefelbein, J

Published Date

  • March 2010

Published In

Volume / Issue

  • 61 / 6

Start / End Page

  • 992 - 1000

PubMed ID

  • 20409273

Pubmed Central ID

  • 20409273

Electronic International Standard Serial Number (EISSN)

  • 1365-313X

International Standard Serial Number (ISSN)

  • 0960-7412

Digital Object Identifier (DOI)

  • 10.1111/j.1365-313X.2010.04129.x

Language

  • eng