Bimodular auxin response controls organogenesis in Arabidopsis.

Published

Journal Article

Like animals, the mature plant body develops via successive sets of instructions that determine cell fate, patterning, and organogenesis. In the coordination of various developmental programs, several plant hormones play decisive roles, among which auxin is the best-documented hormonal signal. Despite the broad range of processes influenced by auxin, how such a single signaling molecule can be translated into a multitude of distinct responses remains unclear. In Arabidopsis thaliana, lateral root development is a classic example of a developmental process that is controlled by auxin at multiple stages. Therefore, we used lateral root formation as a model system to gain insight into the multifunctionality of auxin. We were able to demonstrate the complementary and sequential action of two discrete auxin response modules, the previously described Solitary Root/indole-3-Acetic Acid (IAA)14-Auxin Response Factor (ARF)7-ARF19-dependent lateral root initiation module and the successive Bodenlos/IAA12-Monopteros/ARF5-dependent module, both of which are required for proper organogenesis. The genetic framework in which two successive auxin response modules control early steps of a developmental process adds an extra dimension to the complexity of auxin's action.

Full Text

Duke Authors

Cited Authors

  • De Smet, I; Lau, S; Voss, U; Vanneste, S; Benjamins, R; Rademacher, EH; Schlereth, A; De Rybel, B; Vassileva, V; Grunewald, W; Naudts, M; Levesque, MP; Ehrismann, JS; Inzé, D; Luschnig, C; Benfey, PN; Weijers, D; Van Montagu, MCE; Bennett, MJ; Jürgens, G; Beeckman, T

Published Date

  • February 2010

Published In

Volume / Issue

  • 107 / 6

Start / End Page

  • 2705 - 2710

PubMed ID

  • 20133796

Pubmed Central ID

  • 20133796

Electronic International Standard Serial Number (EISSN)

  • 1091-6490

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.0915001107

Language

  • eng