Skip to main content

FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER

Publication ,  Journal Article
STIMMEL, GL; SKOWRON, DM; CHAMEIDES, WA
Published in: HOSPITAL FORMULARY
August 1991

Recent interest in serotonin's role in the etiology of mood disorders has focused attention on antidepressant drugs that have a specific effect on this neurotransmitter. Fluvoxamine is a very potent and specific inhibitor of the presynaptic reuptake of serotonin. The drug is currently under FDA review for the treatment of major depression and obsessive-compulsive disorder. Results of clinical trials suggest that fluvoxamine is equal in efficacy to tricyclic antidepressants for major depression, and more effective than placebo for obsessive-compulsive disorder. It is much better tolerated than tricyclic antidepressants due to its very low incidence of anticholinergic, cardiac, and sedative effects. Compared with fluoxetine, fluvoxamine offers the advantages of a much shorter half-life of elimination; less potential for agitation, insomnia, and drug interactions; and the possibility of a bedtime dosing regimen. Compared with clomipramine, fluvoxamine may also offer an equally effective and better tolerated treatment for obsessive-compulsive disorder.

Duke Scholars

Published In

HOSPITAL FORMULARY

ISSN

0098-6909

Publication Date

August 1991

Volume

26

Issue

8

Start / End Page

635 / \&
 

Citation

APA
Chicago
ICMJE
MLA
NLM
STIMMEL, G. L., SKOWRON, D. M., & CHAMEIDES, W. A. (1991). FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER. HOSPITAL FORMULARY, 26(8), 635.
STIMMEL, G. L., D. M. SKOWRON, and W. A. CHAMEIDES. “FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER.” HOSPITAL FORMULARY 26, no. 8 (August 1991): 635.
STIMMEL GL, SKOWRON DM, CHAMEIDES WA. FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER. HOSPITAL FORMULARY. 1991 Aug;26(8):635.
STIMMEL, G. L., et al. “FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER.” HOSPITAL FORMULARY, vol. 26, no. 8, Aug. 1991, p. 635.
STIMMEL GL, SKOWRON DM, CHAMEIDES WA. FOCUS ON FLUVOXAMINE - A SEROTONIN REUPTAKE INHIBITOR FOR MAJOR DEPRESSION AND OBSESSIVE-COMPULSIVE DISORDER. HOSPITAL FORMULARY. 1991 Aug;26(8):635.

Published In

HOSPITAL FORMULARY

ISSN

0098-6909

Publication Date

August 1991

Volume

26

Issue

8

Start / End Page

635 / \&