Lessons from two trials of mycophenolate mofetil in myasthenia gravis.

Journal Article (Journal Article)

Two randomized controlled trials of mycophenolate mofetil (MMF) in the treatment of myasthenia gravis (MG) were recently completed. Although neither study demonstrated efficacy of MMF in the population of patients studied, there are valuable lessons in the way these studies were developed and performed. After reviewing the design and results of these trials, we discuss possible reasons leading to negative results and the lessons learned, which should be useful for future clinical trials in MG.

Full Text

Duke Authors

Cited Authors

  • Sanders, DB; Siddiqi, ZA

Published Date

  • 2008

Published In

Volume / Issue

  • 1132 /

Start / End Page

  • 249 - 253

PubMed ID

  • 18567876

International Standard Serial Number (ISSN)

  • 0077-8923

Digital Object Identifier (DOI)

  • 10.1196/annals.1405.031


  • eng

Conference Location

  • United States