Retrospective analysis of the use of cyclosporine in myasthenia gravis.

Journal Article (Journal Article)

The authors reviewed the records of patients with myasthenia gravis who took cyclosporine for at least 6 months between November 1987 and January 1999. Of 57 patients who took cyclosporine for an average of 3.5 years, 55 (96%) had clinical improvement. The median time to best clinical response was 7 months. Corticosteroids were discontinued or decreased in 95% of 38 patients taking them. Major side effects included elevated serum creatinine (28%) and malignancy (11%). Five percent could not afford or tolerate the drug.

Full Text

Duke Authors

Cited Authors

  • Ciafaloni, E; Nikhar, NK; Massey, JM; Sanders, DB

Published Date

  • August 8, 2000

Published In

Volume / Issue

  • 55 / 3

Start / End Page

  • 448 - 450

PubMed ID

  • 10932288

International Standard Serial Number (ISSN)

  • 0028-3878

Digital Object Identifier (DOI)

  • 10.1212/wnl.55.3.448

Language

  • eng

Conference Location

  • United States