Mycophenolate mofetil for myasthenia gravis: an open-label pilot study.
(Clinical Trial;Journal Article)
In an open-label study, 12 patients with refractory MG or who were taking only corticosteroids and required additional immunosuppression received mycophenolate mofetil 1 g twice daily for 6 months. A reduction of three points in a quantified MG score and two points in a manual muscle test or a reduction of 50% in corticosteroid dose defined efficacy. Eight patients improved, beginning after 2 weeks to 2 months. No major side effects were observed.
Ciafaloni, E; Massey, JM; Tucker-Lipscomb, B; Sanders, DB
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