Treatment of myasthenia gravis: current practice and future directions.
Journal Article (Journal Article)
Myasthenia gravis is the best understood of the autoimmune diseases and a number of treatments are currently used to produce clinical improvement. However, due to the scarcity of evidence-based and comparative data, there is still no consensus on many therapeutic issues. Even a widely accepted treatment like thymectomy has never been proven effective by a well-designed trial. These are just some of the unanswered questions: What is the best treatment algorithm and safest long-term management of myasthenia gravis? What patients are likely to benefit from thymectomy? How long should myasthenia gravis patients be treated? Is it possible to discontinue immunotherapy once remission has been achieved? What are the risks associated with long-term immunosuppression? In this article, we review current therapeutic strategies and these unresolved questions about myasthenia gravis treatment.
Full Text
Duke Authors
Cited Authors
- Ciafaloni, E; Sanders, DB
Published Date
- September 2002
Published In
Volume / Issue
- 2 / 5
Start / End Page
- 743 - 748
PubMed ID
- 19810991
Pubmed Central ID
- 19810991
Electronic International Standard Serial Number (EISSN)
- 1744-8360
Digital Object Identifier (DOI)
- 10.1586/14737175.2.5.743
Language
- eng
Conference Location
- England