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Neonatal experimental autoimmune myasthenia gravis.

Publication ,  Journal Article
Sanders, DB; Cobb, EE; Winfield, JB
Published in: Muscle Nerve
1978

Neonatal rats born of and nursed by mothers immunized with Torpedo acetylcholine receptor protein developed a defect of neuromuscular transmission as indicated by reduced miniature endplate potential amplitudes. It is likely that antibodies to the Torpedo receptor protein were passively transferred to the neonates in the milk. With the exception of the route of transfer, this neonatal form of experimental autoimmune myasthenia gravis appears to be similar to its human counterpart, and thus can serve as an experimental model.

Duke Scholars

Published In

Muscle Nerve

DOI

ISSN

0148-639X

Publication Date

1978

Volume

1

Issue

2

Start / End Page

146 / 150

Location

United States

Related Subject Headings

  • Receptors, Cholinergic
  • Rats
  • Pregnancy Complications
  • Pregnancy
  • Neuromuscular Junction
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Membrane Potentials
  • Maternal-Fetal Exchange
  • Fishes
 

Citation

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ICMJE
MLA
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Sanders, D. B., Cobb, E. E., & Winfield, J. B. (1978). Neonatal experimental autoimmune myasthenia gravis. Muscle Nerve, 1(2), 146–150. https://doi.org/10.1002/mus.880010207
Sanders, D. B., E. E. Cobb, and J. B. Winfield. “Neonatal experimental autoimmune myasthenia gravis.Muscle Nerve 1, no. 2 (1978): 146–50. https://doi.org/10.1002/mus.880010207.
Sanders DB, Cobb EE, Winfield JB. Neonatal experimental autoimmune myasthenia gravis. Muscle Nerve. 1978;1(2):146–50.
Sanders, D. B., et al. “Neonatal experimental autoimmune myasthenia gravis.Muscle Nerve, vol. 1, no. 2, 1978, pp. 146–50. Pubmed, doi:10.1002/mus.880010207.
Sanders DB, Cobb EE, Winfield JB. Neonatal experimental autoimmune myasthenia gravis. Muscle Nerve. 1978;1(2):146–150.
Journal cover image

Published In

Muscle Nerve

DOI

ISSN

0148-639X

Publication Date

1978

Volume

1

Issue

2

Start / End Page

146 / 150

Location

United States

Related Subject Headings

  • Receptors, Cholinergic
  • Rats
  • Pregnancy Complications
  • Pregnancy
  • Neuromuscular Junction
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Membrane Potentials
  • Maternal-Fetal Exchange
  • Fishes