Neonatal experimental autoimmune myasthenia gravis.

Journal Article (Journal Article)

Neonatal rats born of and nursed by mothers immunized with Torpedo acetylcholine receptor protein developed a defect of neuromuscular transmission as indicated by reduced miniature endplate potential amplitudes. It is likely that antibodies to the Torpedo receptor protein were passively transferred to the neonates in the milk. With the exception of the route of transfer, this neonatal form of experimental autoimmune myasthenia gravis appears to be similar to its human counterpart, and thus can serve as an experimental model.

Full Text

Duke Authors

Cited Authors

  • Sanders, DB; Cobb, EE; Winfield, JB

Published Date

  • March 1, 1978

Published In

Volume / Issue

  • 1 / 2

Start / End Page

  • 146 - 150

PubMed ID

  • 571528

International Standard Serial Number (ISSN)

  • 0148-639X

Digital Object Identifier (DOI)

  • 10.1002/mus.880010207


  • eng

Conference Location

  • United States