Malignancy after solid organ transplantation: an overview.

Journal Article (Journal Article;Review)

With improving survival following solid organ transplantation, clinicians must be aware of post-transplant complications. One increasingly frequent complication is the development of malignancy after transplantation. The most common malignancies encountered in the post-solid organ transplant setting are nonmelanoma skin cancers, post-transplant lymphoproliferative disorders, and Kaposi's sarcoma (KS). The pathogenesis of these tumors is likely related to the immunosuppressive drugs used post-transplantation and subsequent viral infection. Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft.

Full Text

Duke Authors

Cited Authors

  • Zafar, SY; Howell, DN; Gockerman, JP

Published Date

  • July 2008

Published In

Volume / Issue

  • 13 / 7

Start / End Page

  • 769 - 778

PubMed ID

  • 18614590

International Standard Serial Number (ISSN)

  • 1083-7159

Digital Object Identifier (DOI)

  • 10.1634/theoncologist.2007-0251


  • eng

Conference Location

  • England