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Supportive care in the management of colon cancer.

Publication ,  Journal Article
Morse, MA
Published in: Support Cancer Ther
April 1, 2006

Patients with colorectal cancer present a number of supportive care challenges including those related to the underlying disease, such as gastrointestinal obstruction, nausea, anorexia, and fatigue, and those caused by the treatments, such as oral mucositis, neuropathy, and chemotherapy-induced diarrhea. Unique toxicities can accompany specific routes of administration of colon cancer drugs such as hand-foot syndrome with oral capecitabine and continuous infusion fluorouracil and biliary sclerosis with intrahepatic arterial floxuridine. The newer targeted therapies also present new toxicities, such as cardiovascular events and wound-healing complications with bevacizumab and rash and hypomagnesemia with cetuximab. Recent additions to the therapeutic armamentarium have presented new challenges, such as oxaliplatin-induced peripheral neuropathy, capecitabine-induced hand-foot syndrome, cetuximab-induced rash, and bevacizumab-associated arterial thrombotic events, bowel perforation, hypertension, and wound-healing complications. This article focuses on the prevention and management of several of these more common symptoms and toxicities.

Duke Scholars

Published In

Support Cancer Ther

DOI

ISSN

1543-2912

Publication Date

April 1, 2006

Volume

3

Issue

3

Start / End Page

158 / 170

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Morse, M. A. (2006). Supportive care in the management of colon cancer. Support Cancer Ther, 3(3), 158–170. https://doi.org/10.3816/SCT.2006.n.014
Morse, Michael A. “Supportive care in the management of colon cancer.Support Cancer Ther 3, no. 3 (April 1, 2006): 158–70. https://doi.org/10.3816/SCT.2006.n.014.
Morse MA. Supportive care in the management of colon cancer. Support Cancer Ther. 2006 Apr 1;3(3):158–70.
Morse, Michael A. “Supportive care in the management of colon cancer.Support Cancer Ther, vol. 3, no. 3, Apr. 2006, pp. 158–70. Pubmed, doi:10.3816/SCT.2006.n.014.
Morse MA. Supportive care in the management of colon cancer. Support Cancer Ther. 2006 Apr 1;3(3):158–170.

Published In

Support Cancer Ther

DOI

ISSN

1543-2912

Publication Date

April 1, 2006

Volume

3

Issue

3

Start / End Page

158 / 170

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis