Activating function of needle electrodes in anisotropic tissue.

Journal Article

We present an analytical solution for the electrical potential and activating function (AF) established by cylindrical needle electrodes in anisotropic tissue. We compare this activating function to (1) AF computed assuming line-source electrodes and (2) AF computed using a finite element program. The results show that when the fiber is two needle diameters away from the electrodes, the maximum of the AF for needle electrodes is 1.43-times larger than for line-source electrodes, which results in lower thresholds for stimulation and electroporation. Therefore, for fibers that are close to the stimulating electrodes, one would benefit from using the formula that accounts for the electrodes' geometry.

Full Text

Duke Authors

Cited Authors

  • Guo, L; Cranford, JP; Neu, JC; Neu, WK

Published Date

  • September 2009

Published In

Volume / Issue

  • 47 / 9

Start / End Page

  • 1001 - 1010

PubMed ID

  • 19579040

Pubmed Central ID

  • 19579040

Electronic International Standard Serial Number (EISSN)

  • 1741-0444

International Standard Serial Number (ISSN)

  • 0140-0118

Digital Object Identifier (DOI)

  • 10.1007/s11517-009-0508-2

Language

  • eng