Performance of a new cardiac cryoablation system in the treatment of cavotricuspid valve isthmus-dependent atrial flutter.

Published

Journal Article

We sought to evaluate prospectively the safety and efficacy of cryothermal energy to ablate typical atrial flutter (AFL). Ablation of cardiac tissue using cryothermal energy has recently been developed as an alternative to radiofrequency energy, which may offer certain advantages in the treatment of AFL. This prospective, multicenter nonrandomized study of a new catheter-based system for the treatment of cavotricuspid isthmus (CTI)-dependent AFL enrolled patients between 18 and 75 years of age. The CTI dependence of AFL was confirmed at electrophysiologic study with activation mapping and/or entrainment. Patients with atrial septal defect, recent myocardial infarction, left ventricular ejection fraction <0.30, or prior AFL ablation were excluded. Cryoablation of AFL was performed in 48 patients from 11 centers. The procedure was immediately successful in 45 patients (94%), and effective in 30 of 40 patients with complete data available at 6 months. Cryoablation is a promising new treatment of CTI-dependent AFL refractory to medical therapy. Further improvements in catheter design and intravascular sheaths will be tested in a larger multicenter trial.

Full Text

Duke Authors

Cited Authors

  • Daubert, JP; Hoyt, RH; John, R; Chinitz, L; Martin, DT; Fellows, C; Feld, G; Pelkey, W; Sehra, R; CryoCor Atrial Flutter Investigators,

Published Date

  • January 2005

Published In

Volume / Issue

  • 28 Suppl 1 /

Start / End Page

  • S142 - S145

PubMed ID

  • 15683482

Pubmed Central ID

  • 15683482

International Standard Serial Number (ISSN)

  • 0147-8389

Digital Object Identifier (DOI)

  • 10.1111/j.1540-8159.2005.00094.x

Language

  • eng

Conference Location

  • United States