Basic methods in histopathology of joint tissues.

Journal Article (Journal Article;Review)

Histological and histochemical methods are important tools in the evaluation of joint tissue samples for degenerative joint diseases, both in humans and in animal models. In this respect, standardized, simple, and reliable techniques are mandatory. This chapter describes five basic staining procedures appropriate for macroscopic (Indian ink) and histologic (HE/hematoxylin - eosin) visualization and scoring of cartilage proteoglycan and collagen content (toluidine blue/safranin O and picrosirius red/Goldner's trichrome).

Full Text

Duke Authors

Cited Authors

  • Schmitz, N; Laverty, S; Kraus, VB; Aigner, T

Published Date

  • October 2010

Published In

Volume / Issue

  • 18 Suppl 3 /

Start / End Page

  • S113 - S116

PubMed ID

  • 20864017

Electronic International Standard Serial Number (EISSN)

  • 1522-9653

Digital Object Identifier (DOI)

  • 10.1016/j.joca.2010.05.026


  • eng

Conference Location

  • England