New developments in Sjögren's syndrome.

Journal Article (Review;Journal Article)

The growing number of conditions associated with sicca manifestations and focal sialadenitis has shed further light on the heterogeneity of Sjögren's syndrome. Viral and retroviral infections, lymphoproliferative disorders, as well as various autoimmune syndromes, target the lacrimal and salivary glands and incite a local immune response. This awareness has not only intensified the search for a viral or retroviral cause of Sjögren's syndrome, but it has also provided a daunting challenge to investigators who are striving to improve diagnostic testing and classification. A better understanding of Sjögren's syndrome is needed to develop innovative and more effective therapies.

Full Text

Duke Authors

Cited Authors

  • St Clair, EW

Published Date

  • September 1993

Published In

Volume / Issue

  • 5 / 5

Start / End Page

  • 604 - 612

PubMed ID

  • 8398611

Electronic International Standard Serial Number (EISSN)

  • 1531-6963

International Standard Serial Number (ISSN)

  • 1040-8711

Digital Object Identifier (DOI)

  • 10.1097/00002281-199305050-00008


  • eng