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The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics.

Publication ,  Journal Article
Treatment for Adolescents with Depression Study (TADS) Team,
Published in: J Am Acad Child Adolesc Psychiatry
January 2005

OBJECTIVE: The Treatment for Adolescents With Depression Study is a multicenter, randomized clinical trial sponsored by the NIMH. This study is designed to evaluate the short- and long-term effectiveness of four treatments for adolescents with major depressive disorder: fluoxetine, cognitive-behavioral therapy, their combination, and, acutely, pill placebo. This report describes the demographic and clinical characteristics of the sample and addresses external validity. METHOD: Participants are 439 adolescents, aged 12-17 years inclusively, with a primary DSM-IV diagnosis of current major depressive disorder. Baseline data are summarized and compared with those from national samples and previous trials. RESULTS: The sample composition is 54.4% girls, 73.8% white, 12.5% African American, and 8.9% Hispanic. The mean Child Depression Rating Scale-Revised total score is 60.1 (SD = 10.4, range 45-98) with 86.0% experiencing their first major depressive episode. The most common concurrent diagnoses are generalized anxiety disorder (15.3%), attention-deficit/hyperactivity disorder (13.7%), oppositional defiant disorder (13.2%), social phobia (10.7%), and dysthymia (10.5%). Demographic results are consistent with data from national samples and large psychopharmacology trials involving depressed adolescents. CONCLUSIONS: The Treatment for Adolescents With Depression Study provides a large, diverse, and representative sample of depressed adolescents that highlights the complexity of major depressive disorder in adolescents and provides a rich source for explicating the effects of moderator and mediator variables on baseline psychopathology and treatment outcome.

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Published In

J Am Acad Child Adolesc Psychiatry

DOI

ISSN

0890-8567

Publication Date

January 2005

Volume

44

Issue

1

Start / End Page

28 / 40

Location

United States

Related Subject Headings

  • Substance-Related Disorders
  • Severity of Illness Index
  • Psychotherapy
  • Male
  • Humans
  • Hospitalization
  • Female
  • Diagnostic and Statistical Manual of Mental Disorders
  • Developmental & Child Psychology
  • Depressive Disorder, Major
 

Citation

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Treatment for Adolescents with Depression Study (TADS) Team, . (2005). The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics. J Am Acad Child Adolesc Psychiatry, 44(1), 28–40. https://doi.org/10.1097/01.chi.0000145807.09027.82
Treatment for Adolescents with Depression Study (TADS) Team, M. “The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics.J Am Acad Child Adolesc Psychiatry 44, no. 1 (January 2005): 28–40. https://doi.org/10.1097/01.chi.0000145807.09027.82.
Treatment for Adolescents with Depression Study (TADS) Team. The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics. J Am Acad Child Adolesc Psychiatry. 2005 Jan;44(1):28–40.
Treatment for Adolescents with Depression Study (TADS) Team, M. “The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics.J Am Acad Child Adolesc Psychiatry, vol. 44, no. 1, Jan. 2005, pp. 28–40. Pubmed, doi:10.1097/01.chi.0000145807.09027.82.
Treatment for Adolescents with Depression Study (TADS) Team. The Treatment for Adolescents With Depression Study (TADS): demographic and clinical characteristics. J Am Acad Child Adolesc Psychiatry. 2005 Jan;44(1):28–40.
Journal cover image

Published In

J Am Acad Child Adolesc Psychiatry

DOI

ISSN

0890-8567

Publication Date

January 2005

Volume

44

Issue

1

Start / End Page

28 / 40

Location

United States

Related Subject Headings

  • Substance-Related Disorders
  • Severity of Illness Index
  • Psychotherapy
  • Male
  • Humans
  • Hospitalization
  • Female
  • Diagnostic and Statistical Manual of Mental Disorders
  • Developmental & Child Psychology
  • Depressive Disorder, Major