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Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.

Publication ,  Journal Article
McGovern, PG; Myers, ER; Silva, S; Coutifaris, C; Carson, SA; Legro, RS; Schlaff, WD; Carr, BR; Steinkampf, MP; Giudice, LC; Leppert, PC ...
Published in: Fertil Steril
November 2004

OBJECTIVE: To examine the proportion of cases with proliferative endometrium on biopsies performed after positive home urine LH testing. DESIGN: Multicenter clinical trial of the usefulness of endometrial biopsy in the evaluation of infertility, with women from fertile and infertile couples randomly assigned to midluteal vs. late luteal phase endometrial sampling. SETTING: Twelve clinical sites of the National Institutes of Health/National Institute of Child Health and Human Development-sponsored Reproductive Medicine Network. PATIENT(S): All women in the study had regular menstrual cycles. Fertile volunteers who had delivered a live born infant within the past 2 years without medical intervention were recruited through advertisements at participating sites. Infertile women with regular cycles were recruited from the clinical practices of the sites' physicians. INTERVENTION(S): Interview, informed consent, subject-interpreted home urine LH testing, and endometrial biopsy in either the midluteal or late luteal phase. MAIN OUTCOME MEASURE(S): Proportion of cases with proliferative endometrium on biopsy. RESULT(S): In both fertile and infertile women, more than 7% of endometrial biopsies performed 7-13 days after a positive home urine LH test revealed proliferative endometrium. CONCLUSION(S): Patient interpretation of home urine LH test kits not uncommonly results in false-positive tests. Women planning menstrual cycle testing or procedures related to ovulation may benefit from additional confirmatory testing.

Duke Scholars

Published In

Fertil Steril

DOI

ISSN

0015-0282

Publication Date

November 2004

Volume

82

Issue

5

Start / End Page

1273 / 1277

Location

United States

Related Subject Headings

  • Self Care
  • Obstetrics & Reproductive Medicine
  • Observer Variation
  • Luteinizing Hormone
  • Infertility, Female
  • Humans
  • Female
  • False Positive Reactions
  • Endometrium
  • Biopsy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McGovern, P. G., Myers, E. R., Silva, S., Coutifaris, C., Carson, S. A., Legro, R. S., … NICHD National Cooperative Reproductive Medicine Network, . (2004). Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril, 82(5), 1273–1277. https://doi.org/10.1016/j.fertnstert.2004.03.070
McGovern, Peter G., Evan R. Myers, Susan Silva, Christos Coutifaris, Sandra A. Carson, Richard S. Legro, William D. Schlaff, et al. “Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.Fertil Steril 82, no. 5 (November 2004): 1273–77. https://doi.org/10.1016/j.fertnstert.2004.03.070.
McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, et al. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril. 2004 Nov;82(5):1273–7.
McGovern, Peter G., et al. “Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.Fertil Steril, vol. 82, no. 5, Nov. 2004, pp. 1273–77. Pubmed, doi:10.1016/j.fertnstert.2004.03.070.
McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice LC, Leppert PC, Diamond MP, NICHD National Cooperative Reproductive Medicine Network. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril. 2004 Nov;82(5):1273–1277.
Journal cover image

Published In

Fertil Steril

DOI

ISSN

0015-0282

Publication Date

November 2004

Volume

82

Issue

5

Start / End Page

1273 / 1277

Location

United States

Related Subject Headings

  • Self Care
  • Obstetrics & Reproductive Medicine
  • Observer Variation
  • Luteinizing Hormone
  • Infertility, Female
  • Humans
  • Female
  • False Positive Reactions
  • Endometrium
  • Biopsy