Recovery of function after brain damage: facilitation by the calcium entry blocker nimodipine.


Journal Article

Large neocortical injuries can interfere with the initial performance of many previously learned behaviors. This dysfunction, however, may not be attributable to the loss of the memories of learned behaviors but to a failure to access memories that are spared. The results of this experiment support this hypothesis by demonstrating that the calcium entry blocker nimodipine, which prevents trauma-induced retrograde amnesia in a 1-trial passive learning situation, will also facilitate the recovery of pre-operatively learned brightness discrimination in rats with visual neocortical injuries.

Full Text

Duke Authors

Cited Authors

  • LeVere, TE; Brugler, T; Sandin, M; Gray-Silva, S

Published Date

  • June 1989

Published In

Volume / Issue

  • 103 / 3

Start / End Page

  • 561 - 565

PubMed ID

  • 2736070

Pubmed Central ID

  • 2736070

Electronic International Standard Serial Number (EISSN)

  • 1939-0084

International Standard Serial Number (ISSN)

  • 0735-7044

Digital Object Identifier (DOI)

  • 10.1037//0735-7044.103.3.561


  • eng