Vasospasm in children with traumatic brain injury.
Journal Article (Journal Article)
Objective
To determine the incidence of vasospasm in children who have suffered moderate to severe traumatic brain injury.Methods
A prospective observational pilot study in a 24-bed pediatric intensive care unit was performed. Twenty-two children aged 7 months to 14 years with moderate to severe traumatic brain injury as indicated by Glasgow Coma Score 120 cm/s were considered to have vasospasm by criterion A. If flow velocity in the MCA was >120 cm/s and the Lindegaard ratio was >3, vasospasm was considered to be present by criterion B. Patients with basilar artery (BA) flow velocity >90 cm/s met criteria for vasospasm in the posterior circulation (criterion C).Results
In the MCA, 45.5% of patients developed vasospasm based on criterion A and 36.3% developed vasospasm based on criterion B. A total of 18.2% of patients developed vasospasm in the BA by criterion C. Typical day of onset of vasospasm was hospital day 2-3. Duration of vasospasm in the anterior circulation was 4 +/- 2 days based on criteria A and 3 +/- 1 days based on criteria B. Vasospasm in the posterior circulation persisted for 2 +/- 1 days.Conclusions
Using the adult criteria outlined above to diagnose vasospasm, a significant proportion of pediatric patients who have suffered moderate to severe traumatic brain injury develop vasospasm during the course of their treatment.Full Text
Duke Authors
Cited Authors
- O'Brien, NF; Reuter-Rice, KE; Khanna, S; Peterson, BM; Quinto, KB
Published Date
- April 2010
Published In
Volume / Issue
- 36 / 4
Start / End Page
- 680 - 687
PubMed ID
- 20091024
Pubmed Central ID
- PMC2837183
Electronic International Standard Serial Number (EISSN)
- 1432-1238
International Standard Serial Number (ISSN)
- 0342-4642
Digital Object Identifier (DOI)
- 10.1007/s00134-009-1747-2
Language
- eng