The role of bacterial DNA in autoantibody induction.
Journal Article (Journal Article;Review)
Bacterial DNA has potent immunological properties that can stimulate the immune system in SLE in both specific and non-specific ways. As such, this molecule may play an important role in disease pathogenesis, because it can exert immunomodulatory activity and function as a molecular mimic. Future studies will hopefully both determine the role of foreign nucleic acids in the induction of autoantibodies and lead to strategies for their elimination.
- Pisetsky, DS
Volume / Issue
- 247 /
Start / End Page
- 143 - 155
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)