The role of bacterial DNA in autoantibody induction.

Journal Article (Journal Article;Review)

Bacterial DNA has potent immunological properties that can stimulate the immune system in SLE in both specific and non-specific ways. As such, this molecule may play an important role in disease pathogenesis, because it can exert immunomodulatory activity and function as a molecular mimic. Future studies will hopefully both determine the role of foreign nucleic acids in the induction of autoantibodies and lead to strategies for their elimination.

Full Text

Duke Authors

Cited Authors

  • Pisetsky, DS

Published Date

  • 2000

Published In

Volume / Issue

  • 247 /

Start / End Page

  • 143 - 155

PubMed ID

  • 10689785

International Standard Serial Number (ISSN)

  • 0070-217X

Digital Object Identifier (DOI)

  • 10.1007/978-3-642-59672-8_10

Language

  • eng

Conference Location

  • Germany