Systemic lupus erythematosus.

Journal Article (Journal Article;Review)

Systemic lupus erythematosus is a prototypic autoimmune disease characterized by antinuclear antibody production. In recent investigations, the contributions of various polymorphic immune response gene systems to disease pathogenesis have been analyzed. Unique cellular and molecular studies have also established the role of 'autoantigen drive' in autoantibody induction and its relationship to polyclonal B-cell activation.

Full Text

Duke Authors

Cited Authors

  • Pisetsky, DS

Published Date

  • December 1991

Published In

Volume / Issue

  • 3 / 6

Start / End Page

  • 917 - 923

PubMed ID

  • 1793536

International Standard Serial Number (ISSN)

  • 0952-7915

Digital Object Identifier (DOI)

  • 10.1016/s0952-7915(05)80014-7


  • eng

Conference Location

  • England