Bleeding per vaginam is associated with funisitis in women with preterm prelabour rupture of the fetal membranes.

Journal Article (Journal Article)

OBJECTIVE: To evaluate the risk of funisitis among women with preterm prelabour rupture of the membranes (PPROM) and subsequent bleeding per vaginam. DESIGN: Prospective cohort study. SETTING: A University Hospital in the USA. POPULATION: A total of 157 women with PPROM, divided into those with bleeding per vaginam during the hospital admission (n = 46) and those without bleeding per vaginam (n = 111). METHODS: Pathologist blinded to bleeding status assessed placental pathology for funisitis. MAIN OUTCOME MEASURES: Funisitis. RESULTS: Women with bleeding per vaginam were more likely to have funisitis (67.4% versus 36%, P < 0.001) compared with those without bleeding. Logistic regression demonstrated that bleeding per vaginam predicted funisitis after controlling for gestational age at admission, latency period and gestational age at delivery. CONCLUSIONS: Among women with PPROM, those with bleeding per vaginam are more likely to have funisitis than those without bleeding per vaginam.

Full Text

Duke Authors

Cited Authors

  • Grotegut, CA; Johnson, LNC; Fitzpatrick, CB; Heine, RP; Swamy, GK; Murtha, AP

Published Date

  • May 2011

Published In

Volume / Issue

  • 118 / 6

Start / End Page

  • 735 - 740

PubMed ID

  • 21392243

Pubmed Central ID

  • PMC3075338

Electronic International Standard Serial Number (EISSN)

  • 1471-0528

Digital Object Identifier (DOI)

  • 10.1111/j.1471-0528.2011.02911.x


  • eng

Conference Location

  • England