Current immunotherapeutic strategies in malignant melanoma.

Journal Article (Journal Article;Review)

The basis of immunotherapy for melanoma is the existence of melanoma-associated antigens that can be targeted by the immune system. Identification of many of these antigens has enabled investigators to develop a wide array of immunotherapy strategies for the treatment of melanoma. Although several of these strategies have been shown to induce antitumor immune responses in some patients, robust clinical responses have been observed less frequently. With exciting recent advancements in this field, however, there is promise of generating potent immunologic responses and translating them more consistently into durable clinical responses. This article reviews several current approaches to immunotherapy for melanoma and describes the key role that surgeons play in advancing this area of oncology.

Full Text

Duke Authors

Cited Authors

  • Agostino, NM; Ali, A; Nair, SG; Mosca, PJ

Published Date

  • October 2007

Published In

Volume / Issue

  • 16 / 4

Start / End Page

  • 945 - xi

PubMed ID

  • 18022553

International Standard Serial Number (ISSN)

  • 1055-3207

Digital Object Identifier (DOI)

  • 10.1016/j.soc.2007.07.010


  • eng

Conference Location

  • United States