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Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1).

Publication ,  Journal Article
Martin, SS; Hollingsworth, CL; Norfolk, SG; Wolfe, CR; Hollingsworth, JW
Published in: Chest
May 2010

Historical influenza A epidemics have carried elevated rates of cardiovascular disease, including transient cardiac dysfunction. Whether such an association holds for the novel influenza A strain, pandemic 2009 influenza A(H1N1) [A(H1N1)], remains unknown. We report an index case of transient cardiac dysfunction associated with A(H1N1) infection. Next, we reviewed 123 sequential cases of patients hospitalized with pandemic A(H1N1) at a single academic medical center in the United States from April 1, 2009, through October 31, 2009. We identified that 4.9% (6/123) of patients had either new or worsened left ventricular dysfunction. These cases ranged in age from 23 to 51 years, and all had preexisting medical conditions. ICU level care was required in 83% (5/6) of the cases. Sixty-seven percent (4/6) of the cases had follow-up echocardiograms, and left ventricular function improved in all four. We conclude that potentially reversible cardiac dysfunction is a relatively common complication associated with hospitalized pandemic A(H1N1) influenza.

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Published In

Chest

DOI

EISSN

1931-3543

Publication Date

May 2010

Volume

137

Issue

5

Start / End Page

1195 / 1197

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Retrospective Studies
  • Respiratory System
  • Middle Aged
  • Male
  • Influenza, Human
  • Influenza A Virus, H1N1 Subtype
  • Humans
  • Heart
  • Female
 

Citation

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Martin, S. S., Hollingsworth, C. L., Norfolk, S. G., Wolfe, C. R., & Hollingsworth, J. W. (2010). Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1). Chest, 137(5), 1195–1197. https://doi.org/10.1378/chest.10-0032
Martin, Seth S., Caroline L. Hollingsworth, Stephanie G. Norfolk, Cameron R. Wolfe, and John W. Hollingsworth. “Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1).Chest 137, no. 5 (May 2010): 1195–97. https://doi.org/10.1378/chest.10-0032.
Martin SS, Hollingsworth CL, Norfolk SG, Wolfe CR, Hollingsworth JW. Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1). Chest. 2010 May;137(5):1195–7.
Martin, Seth S., et al. “Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1).Chest, vol. 137, no. 5, May 2010, pp. 1195–97. Pubmed, doi:10.1378/chest.10-0032.
Martin SS, Hollingsworth CL, Norfolk SG, Wolfe CR, Hollingsworth JW. Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1). Chest. 2010 May;137(5):1195–1197.

Published In

Chest

DOI

EISSN

1931-3543

Publication Date

May 2010

Volume

137

Issue

5

Start / End Page

1195 / 1197

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Retrospective Studies
  • Respiratory System
  • Middle Aged
  • Male
  • Influenza, Human
  • Influenza A Virus, H1N1 Subtype
  • Humans
  • Heart
  • Female