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Screening experiments and the use of fractional factorial designs in behavioral intervention research.

Publication ,  Journal Article
Nair, V; Strecher, V; Fagerlin, A; Ubel, P; Resnicow, K; Murphy, S; Little, R; Chakraborty, B; Zhang, A
Published in: American journal of public health
August 2008

Health behavior intervention studies have focused primarily on comparing new programs and existing programs via randomized controlled trials. However, numbers of possible components (factors) are increasing dramatically as a result of developments in science and technology (e.g., Web-based surveys). These changes dictate the need for alternative methods that can screen and quickly identify a large set of potentially important treatment components. We have developed and implemented a multiphase experimentation strategy for accomplishing this goal. We describe the screening phase of this strategy and the use of fractional factorial designs (FFDs) in studying several components economically. We then use 2 ongoing behavioral intervention projects to illustrate the usefulness of FFDs. FFDs should be supplemented with follow-up experiments in the refining phase so any critical assumptions about interactions can be verified.

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Published In

American journal of public health

DOI

EISSN

1541-0048

ISSN

0090-0036

Publication Date

August 2008

Volume

98

Issue

8

Start / End Page

1354 / 1359

Related Subject Headings

  • Tamoxifen
  • Smoking Cessation
  • Randomized Controlled Trials as Topic
  • Public Health
  • Male
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Health Behavior
  • Female
  • Factor Analysis, Statistical
 

Citation

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Nair, V., Strecher, V., Fagerlin, A., Ubel, P., Resnicow, K., Murphy, S., … Zhang, A. (2008). Screening experiments and the use of fractional factorial designs in behavioral intervention research. American Journal of Public Health, 98(8), 1354–1359. https://doi.org/10.2105/ajph.2007.127563
Nair, Vijay, Victor Strecher, Angela Fagerlin, Peter Ubel, Kenneth Resnicow, Susan Murphy, Roderick Little, Bibhas Chakraborty, and Aijun Zhang. “Screening experiments and the use of fractional factorial designs in behavioral intervention research.American Journal of Public Health 98, no. 8 (August 2008): 1354–59. https://doi.org/10.2105/ajph.2007.127563.
Nair V, Strecher V, Fagerlin A, Ubel P, Resnicow K, Murphy S, et al. Screening experiments and the use of fractional factorial designs in behavioral intervention research. American journal of public health. 2008 Aug;98(8):1354–9.
Nair, Vijay, et al. “Screening experiments and the use of fractional factorial designs in behavioral intervention research.American Journal of Public Health, vol. 98, no. 8, Aug. 2008, pp. 1354–59. Epmc, doi:10.2105/ajph.2007.127563.
Nair V, Strecher V, Fagerlin A, Ubel P, Resnicow K, Murphy S, Little R, Chakraborty B, Zhang A. Screening experiments and the use of fractional factorial designs in behavioral intervention research. American journal of public health. 2008 Aug;98(8):1354–1359.

Published In

American journal of public health

DOI

EISSN

1541-0048

ISSN

0090-0036

Publication Date

August 2008

Volume

98

Issue

8

Start / End Page

1354 / 1359

Related Subject Headings

  • Tamoxifen
  • Smoking Cessation
  • Randomized Controlled Trials as Topic
  • Public Health
  • Male
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Health Behavior
  • Female
  • Factor Analysis, Statistical